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According to the NIH, “in most cases, the cause of RLS is unknown,” though “it may have a genetic component.” Nevertheless, experts do have some inkling of the cause, as the NIH reports on their website: Considerable evidence suggests that RLS is related to a dysfunction in the brain’s basal ganglia circuits that use the neurotransmitter dopamine, which is needed to produce smooth, purposeful muscle activity and movement.

Disruption of these pathways frequently results in involuntary movements.

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Cryoconservation of animal genetic resources is a practice that calls for the collection of genetic material in efforts for conservation of a particular breed.

Depending on the species, spermatozoa can fertilize ova externally or internally.

This cycle repeats throughout the night, writes au Technology Editor Peter Farquhar, and “it’s not unusual for people who suffer RLS …

to describe it as torturous.” So why do some people’s legs do this?